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One-Pot Catalytic Enantioselective Domino Nitro-Michael/Michael Synthesis of Cyclopentanes with Four Stereocenters
Journal article   Peer reviewed

One-Pot Catalytic Enantioselective Domino Nitro-Michael/Michael Synthesis of Cyclopentanes with Four Stereocenters

Gui-Ling Zhao, Ismail Ibrahem, Pawel Dziedzic, Junliang Sun, Charlotte Bonneau and Armando Cordova
Chemistry : a European journal, Vol.14(32), pp.10007-10011
01/01/2008
PMID: 18830983

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
A highly enantioselective organocatalytic one-pot synthesis of nitro-, formyl-, and ester-functionalized cyclopentanes with four stereocenters is presented. The cyclopentanes were formed as a predominant diasteroisomer and isolated in high yields with 97-99% ee.

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