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Comparing the Clinical Severity of Disease Caused by Enteroviruses and Human Parechoviruses in Neonates and Infants
Journal article   Peer reviewed

Comparing the Clinical Severity of Disease Caused by Enteroviruses and Human Parechoviruses in Neonates and Infants

Sally Black, Carina Bradley, Florence Y Lai, Savitha Shenoy, Srini Bandi, David J Allen and Julian W Tang
The Pediatric infectious disease journal, Vol.38(2), pp.e36-e38
02/2019
PMID: 30001232

Abstract

Cerebrospinal Fluid - virology Enterovirus - isolation & purification Enterovirus Infections - pathology Female Hospitalization Humans Infant Infant, Newborn Male Parechovirus - isolation & purification Picornaviridae Infections - pathology
Comparison of children hospitalized with enterovirus or human parechovirus (HPeV) detected in their cerebrospinal fluid revealed that HPeV infections presented with more persistent fever, irritability and feeding problems, more frequent leukopenia and lymphopenia and higher admission rates to high dependency or intensive care units. Few HPeV cases were followed up, further studies on long-term outcomes are needed.

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