CMV and Immunosenescence: from basics to clinics

Rafael Solana; Raquel Tarazona; Allison E. Aiello; Arne N. Akbar; Victor Appay; Mark Beswick; Jos A. Bosch; Carmen Campos; Sara Cantisan; Luka Cicin-Sain; Evelyna Derhovanessian; Sara Ferrando-Martinez; Daniela Frasca; Tamas Fuloep; Sheila Govind; Beatrix Grubeck-Loebenstein; Ann Hill; Mikko Hurme; Florian Kern; Anis Larbi; Miguel Lopez-Botet; Andrea B. Maier; Janet E. McElhaney; Paul Moss; Elissaveta Naumova; Janko Nikolich-Zugich; Alejandra Pera; Jerrald L. Rector; Natalie Riddell; Beatriz Sanchez-Correa; Paolo Sansoni; Delphine Sauce; Rene van Lier; George C. Wang; Mark R. Wills; Maciej Zielinski; Graham Pawelec

doi:10.1186/1742-4933-9-23

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CMV and Immunosenescence: from basics to clinics

Journal article

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CMV and Immunosenescence: from basics to clinics

Rafael Solana, Raquel Tarazona, Allison E. Aiello, Arne N. Akbar, Victor Appay, Mark Beswick, Jos A. Bosch, Carmen Campos, Sara Cantisan, Luka Cicin-Sain, …

Immunity & ageing, Vol.9(1), pp.23-23

31/10/2012

DOI: https://doi.org/10.1186/1742-4933-9-23

PMID: 23114110

Abstract

Geriatrics & Gerontology

Immunology

Life Sciences & Biomedicine

Science & Technology

Alone among herpesviruses, persistent Cytomegalovirus (CMV) markedly alters the numbers and proportions of peripheral immune cells in infected-vs-uninfected people. Because the rate of CMV infection increases with age in most countries, it has been suggested that it drives or at least exacerbates "immunosenescence". This contention remains controversial and was the primary subject of the Third International Workshop on CMV & Immunosenescence which was held in Cordoba, Spain, 15-16th March, 2012. Discussions focused on several main themes including the effects of CMV on adaptive immunity and immunosenescence, characterization of CMV-specific T cells, impact of CMV infection and ageing on innate immunity, and finally, most important, the clinical implications of immunosenescence and CMV infection. Here we summarize the major findings of this workshop.

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Title: CMV and Immunosenescence: from basics to clinics
Creators: Rafael Solana - Instituto Maimónides de Investigación Biomédica de Córdoba
Raquel Tarazona - Universidad de Extremadura
Allison E. Aiello - University of Michigan–Ann Arbor
Arne N. Akbar - University College London
Victor Appay - Inserm
Mark Beswick - University of Birmingham
Jos A. Bosch - University of Amsterdam
Carmen Campos - Instituto Maimónides de Investigación Biomédica de Córdoba
Sara Cantisan - University of Córdoba
Luka Cicin-Sain - Helmholtz Ctr Infect Res, Dept Vaccinol & Appl Microbiol, Braunschweig, Germany
Evelyna Derhovanessian - University of Tübingen
Sara Ferrando-Martinez - Univ Gregorio Maranon, Gen Hosp, Lab Mol Immune Biol, Madrid, Spain
Daniela Frasca - University of Miami
Tamas Fuloep - Res Ctr Aging, Sherbrooke, PQ, Canada
Sheila Govind - Cranfield University
Beatrix Grubeck-Loebenstein - Univ Innsbruck, Inst Biomed Aging Res, A-6020 Innsbruck, Austria
Ann Hill - Oregon Health & Science University
Mikko Hurme - Tampere University
Florian Kern - Brighton and Sussex Medical School
Anis Larbi - Singapore Immunology Network
Miguel Lopez-Botet - Univ Pompeu Fabra, Hosp del Mar, Res Inst, IMIM, Barcelona, Spain
Andrea B. Maier - Leiden University Medical Center
Janet E. McElhaney - University of British Columbia
Paul Moss - University of Birmingham
Elissaveta Naumova - Alexandrovska Hospital
Janko Nikolich-Zugich - University of Arizona
Alejandra Pera - Instituto Maimónides de Investigación Biomédica de Córdoba
Jerrald L. Rector - University of Birmingham
Natalie Riddell - University College London
Beatriz Sanchez-Correa - Universidad de Extremadura
Paolo Sansoni - University of Parma
Delphine Sauce - Inserm
Rene van Lier - University of Amsterdam
George C. Wang - Johns Hopkins University
Mark R. Wills - University of Cambridge
Maciej Zielinski - Gdańsk Medical University
Graham Pawelec - University of Tübingen
Publication Details: Immunity & ageing, Vol.9(1), pp.23-23
Publisher: Springer Nature
Number of pages: 9
Date published: 31/10/2012
Grant note: University of Cordoba R21AI096446 / NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID) BB/H020519/1 / Biotechnology and Biological Sciences Research Council; UK Research & Innovation (UKRI); Biotechnology and Biological Sciences Research Council (BBSRC) R01AG020719; R01AG032576 / NATIONAL INSTITUTE ON AGING; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Aging (NIA) BB/H020519/1 / BBSRC; UK Research & Innovation (UKRI); Biotechnology and Biological Sciences Research Council (BBSRC) SAF2011-16169-E / Spanish Ministry of Science; Ministry of Science and Innovation, Spain (MICINN); Spanish Government
Identifiers: 99928765802346
Academic Unit: School of Biosciences
Language: English
Resource Type: Journal article

CMV and Immunosenescence: from basics to clinics

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