Current and future missions such as JUICE and Europa Clipper will attempt to answer long-standing questions regarding the presence and composition of liquid subsurface oceans below the crusts of Jupiter's icy moons. To achieve their scientific objectives, such missions require complex trajectories in the vicinity of multiple large bodies. In support of moon tour design, the tri-circular restricted five-body problem has been introduced in previous work to model the Jupiter-Io-Europa-Ganymede system while exploiting the Laplace resonance of these Galilean moons, allowing for a non-autonomous periodic dynamical system to be defined in which periodic and quasi-periodic orbits, and their associated invariant manifolds, have been shown to exist. In this paper we demonstrate the trajectory design benefits of the tri-circular problem via the generation of a variety of low-energy transfers between libration orbits at Europa and Ganymede. This is achieved by investigating regions of overlap in the stable and unstable manifolds of the desired departure and arrival orbits in the planar case of the tri-circular problem. Transfers were found with ∆V costs as low as 500 m/s and times of flight as low as 30 days.