Abstract
The reproducibility of clinical trial results is of major importance in nutrition research. Variability in the results of apparently similar dietary studies has been previously reported(Reference Sorkin, Kuszak and Williamson1), due to differences in study design, assessment methods, participants’ background diet and inter-individual variability. However, comparisons of identical dietary interventions performed in the same participants, which will control for some of the mentioned variability, are rare. This study aims to assess the reproducibility of an identical dietary intervention (Reading, Imperial, Surrey Saturated fat Cholesterol Intervention study 1 and 2, RISSCI-1 and RISSCI-2) performed on two occasions, on the outcomes of fasted lipids.