Abstract
Rationale for the dietary guideline to replace saturated (SFA) with unsaturated fatty acids (UFA) to reduce risk of atherosclerotic cardiovascular disease (ASCVD) rests heavily on the lowering of serum low density lipoprotein cholesterol (LDL-C)(Reference Mensink1). However, there is evidence to suggest that this dietary exchange may be associated with favourable effects on other cardiometabolic risk factors, including non-high-density lipoprotein-cholesterol (non-HDL-C), a measure of all atherogenic lipoproteins in serum(Reference Pinart, Jeran and Boeing2). The aim of this study was to determine the effects of dietary SFA on serum HDL-C, non-HDL-C, and remnant-cholesterol in the RISSCI-1 study.