IS990, a new species-specific insertion-sequence-related element of the Mycobacterium tuberculosis complex

J Dziadek; A Sajduda; J W Dale; J J McFadden

doi:10.1099/00221287-144-12-3407

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IS990, a new species-specific insertion-sequence-related element of the Mycobacterium tuberculosis complex

Journal article

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IS990, a new species-specific insertion-sequence-related element of the Mycobacterium tuberculosis complex

J Dziadek, A Sajduda, J W Dale and J J McFadden

Microbiology (Society for General Microbiology), Vol.144 ( Pt 12)(12), pp.3407-3412

01/12/1998

DOI: https://doi.org/10.1099/00221287-144-12-3407

PMID: 9884233

Abstract

Amino Acid Sequence

Base Sequence

DNA Transposable Elements - genetics

DNA, Bacterial - analysis

Gene Dosage

Molecular Sequence Data

Mycobacterium tuberculosis - classification

Mycobacterium tuberculosis - genetics

Sequence Homology, Amino Acid

Sequence Homology, Nucleic Acid

Species Specificity

The structure and distribution of 1S990, a new Mycobacterium tuberculosis DNA sequence with homology to characterized insertion sequences (ISs), were investigated. IS990 was related to IS elements of the IS3 family and was present as a single copy in all 21 investigated M. tuberculosis strains, two Mycobacterium bovis strains and two M. bovis BCG strains. The sequence appears to be specific for the M. tuberculosis complex. The element carries two frameshift mutations and appears to be defective.

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Title: IS990, a new species-specific insertion-sequence-related element of the Mycobacterium tuberculosis complex
Creators: J Dziadek - Polish Academy of Sciences
A Sajduda - Department of Genetics of Microorganisms, University of Ldz, Banacha 12/16, 93237 Ldz, Poland.
J W Dale - University of Surrey
J J McFadden - Molecular Microbiology Group, School of Biological Sciences, University of Surrey, Guildford GU2 5XH, UK
Publication Details: Microbiology (Society for General Microbiology), Vol.144 ( Pt 12)(12), pp.3407-3412
Date published: 01/12/1998
Identifiers: 99783525602346
Academic Unit: School of Biosciences
Language: English
Resource Type: Journal article

IS990, a new species-specific insertion-sequence-related element of the Mycobacterium tuberculosis complex

Abstract

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