Climate change is becoming increasingly more pronounced every day while the amount of greenhouse gases in the atmosphere continues to rise. CO₂ reduction to valuable chemicals is an approach which has gathered substantial attention as a means to recycle these gases. Herein we explore some of the tandem catalysis approaches that can be used to achieve transformation of CO₂ to C-C coupled products, focusing especially on tandem catalytic schemes where there is a big opportunity to improve performance by designing effective catalytic nanoreactors. Recent reviews have highlighted the technical challenges and opportunities for advancing tandem catalysis, especially highlighting the need for elucidating structure-activity relationships and mechanisms of reaction through theoretical and in situ/operando characterization techniques ^[1–3]. In this review, we focus on nanoreactor synthesis strategies as a critical research direction, and discuss these in the context of two main tandem pathways (CO-mediated pathway and Methanol-mediated pathway) to C-C coupled products.