This paper examines how universities’ knowledge exchange (KE) profiles evolve in relation to changes in the composition of their funding sources. Using the dynamic capabilities framework as a conceptual lens, we examine how changes in the share of KE versus research income in a university’s financial portfolio are related to the mix of KE channels it uses and of types of stakeholders it engages with, that is, its KE profile. Relying on an 8-year panel of 110 UK-based universities we show that, universities whose share of KE income is higher relative to others, are associated with a higher degree specialization in both KE channels and stakeholder types. Conversely, universities whose share of blue-sky research income is higher relative to others, are associated with greater diversification in both. Some of these linkages are negatively moderated by higher levels of tangible and intangible resources: universities with greater intangible resources are less responsive to variations in research and KE income shares on KE channel diversity; while universities with higher tangible resources are less responsive to variations in research income share on KE stakeholder diversity.