Antiplasmodial diterpenoid from the leaves of Hyptis suaveolens.

JC Chukwujekwu; P Smith; PH Coombes; DA Mulholland; J van Staden

doi:10.1016/j.jep.2005.08.018

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Antiplasmodial diterpenoid from the leaves of Hyptis suaveolens.

Journal article

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Antiplasmodial diterpenoid from the leaves of Hyptis suaveolens.

JC Chukwujekwu, P Smith, PH Coombes, DA Mulholland and J van Staden

J Ethnopharmacol, Vol.102(2), pp.295-297

14/11/2005

DOI: https://doi.org/10.1016/j.jep.2005.08.018

Abstract

Animals

Antimalarials

Diterpenes

Hyptis

Plant Leaves

Plasmodium falciparum

Bioactivity-guided fractionation of the petroleum ether extract of the leaves of Hyptis suaveolens, widely used in Traditional Medicine, has led to the isolation of an abietane-type diterpenoid endoperoxide, 13 alpha-epi-dioxiabiet-8(14)-en-18-ol, displaying high antiplasmodial activity (IC(50) 0.1 microg/ml).

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Title: Antiplasmodial diterpenoid from the leaves of Hyptis suaveolens.
Creators: JC Chukwujekwu
P Smith
PH Coombes
DA Mulholland
J van Staden
Publication Details: J Ethnopharmacol, Vol.102(2), pp.295-297
Date published: 14/11/2005
Date submitted: 17/05/2017
Identifiers: 99516297902346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

Antiplasmodial diterpenoid from the leaves of Hyptis suaveolens.

Abstract

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