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Differential effects of long-chain fatty acids and clofibrate on gene expression profiles in cardiomyocytes.
Journal article   Open access  Peer reviewed

Differential effects of long-chain fatty acids and clofibrate on gene expression profiles in cardiomyocytes.

I Khodadadi, Bruce Griffin and Alfred Thumser
Arch Iran Med, Vol.11(1), pp.42-49
01/2008

Abstract

Analysis of Variance Cells Cultured Clofibrate Fatty Acids Gene Expression Regulation Myocytes Cardiac Reverse Transcriptase Polymerase Chain Reaction Transcription Factors
The link between dietary fat and coronary heart disease has attracted much attention since the effect of long-chain fatty acids on gene transcription has been established. The aim of this study was to investigate the effects of long-chain fatty acids and clofibrate on mRNA levels of specific lipid metabolism-related genes and to determine their effects on global transcriptome levels in a cardiovascular cell-line.
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