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Biophysical characteristics reveal neural stem cell differentiation potential.
Journal article   Open access  Peer reviewed

Biophysical characteristics reveal neural stem cell differentiation potential.

FH Labeed, J Lu, HJ Mulhall, SA Marchenko, KF Hoettges, LC Estrada, AP Lee, MP Hughes and LA Flanagan
PLoS One, Vol.6(9), pp.e25458-?
2011

Abstract

Distinguishing human neural stem/progenitor cell (huNSPC) populations that will predominantly generate neurons from those that produce glia is currently hampered by a lack of sufficient cell type-specific surface markers predictive of fate potential. This limits investigation of lineage-biased progenitors and their potential use as therapeutic agents. A live-cell biophysical and label-free measure of fate potential would solve this problem by obviating the need for specific cell surface markers.
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http://dx.doi.org/10.1371/journal.pone.0025458View
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