In utero administration of Ad5 and AAV pseudotypes to the fetal brain leads to efficient, widespread and long-term gene expression

AA Rahim; AM Wong; S Ahmadi; K Hoefer; SMK Buckley; DA Hughes; AN Nathwani; AH Baker; JH McVey; JD Cooper; SN Waddington

doi:10.1038/gt.2011.157

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In utero administration of Ad5 and AAV pseudotypes to the fetal brain leads to efficient, widespread and long-term gene expression

Journal article

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In utero administration of Ad5 and AAV pseudotypes to the fetal brain leads to efficient, widespread and long-term gene expression

AA Rahim, AM Wong, S Ahmadi, K Hoefer, SMK Buckley, DA Hughes, AN Nathwani, AH Baker, JH McVey, JD Cooper, …

GENE THERAPY, Vol.19(9), pp.936-946

01/09/2012

DOI: https://doi.org/10.1038/gt.2011.157

Abstract

Science & Technology

Life Sciences & Biomedicine

Biochemistry & Molecular Biology

Biotechnology & Applied Microbiology

Genetics & Heredity

Medicine

Research & Experimental

Research & Experimental Medicine

BIOCHEMISTRY & MOLECULAR BIOLOGY

BIOTECHNOLOGY & APPLIED MICROBIOLOGY

GENETICS & HEREDITY

MEDICINE

RESEARCH & EXPERIMENTAL

adenovirus

adeno-associated virus

fetal brain

pseudotypes

gene delivery

ADENOASSOCIATED VIRUS VECTORS

HUMAN-FACTOR-IX

NEURONAL CEROID-LIPOFUSCINOSIS

LETHAL GAUCHER-DISEASE

CENTRAL-NERVOUS-SYSTEM

MOUSE-BRAIN

ANATOMICAL CHARACTERIZATION

LENTIVIRAL VECTORS

NONHUMAN PRIMATE

NEONATAL MICE

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Title: In utero administration of Ad5 and AAV pseudotypes to the fetal brain leads to efficient, widespread and long-term gene expression
Creators: AA Rahim
AM Wong
S Ahmadi
K Hoefer
SMK Buckley
DA Hughes
AN Nathwani
AH Baker
JH McVey
JD Cooper
SN Waddington
Publication Details: GENE THERAPY, Vol.19(9), pp.936-946
Publisher: NATURE PUBLISHING GROUP
Date published: 01/09/2012
Date submitted: 17/05/2017
Identifiers: 99513863902346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

In utero administration of Ad5 and AAV pseudotypes to the fetal brain leads to efficient, widespread and long-term gene expression

Abstract

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