Abstract
Due to its strong correlation with the pathophysiology of many diseases, information about human redblood cells (RBCs) has a crucial function in hematology. Therefore, measuring and understanding themorphological, chemical, and mechanical properties of individual RBCs is a key to understanding thepathophysiology of a number of diseases in hematology, as well as to opening up new possibilities fordiagnosing diseases in their early stages. In this study, we present the simultaneous and quantitativemeasurement of the morphological, chemical, and mechanical parameters of individual RBCs employingoptical holographic microtomography. In addition, it is demonstrated that the correlation analyses of theseRBC parameters provide unique information for distinguishing and understanding diseases.