Emotional Impairment and Persistent Upregulation of mGlu(5) Receptor following Morphine Abstinence: Implications of an mGlu(5)-MOPr Interaction

P Zanos; P Georgiou; LR Gonzalez; S Hourani; Y Chen; I Kitchen; BL Kieffer; R Winsky-Sommerer; A Bailey

doi:10.1093/ijnp/pyw011

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Emotional Impairment and Persistent Upregulation of mGlu(5) Receptor following Morphine Abstinence: Implications of an mGlu(5)-MOPr Interaction

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Emotional Impairment and Persistent Upregulation of mGlu(5) Receptor following Morphine Abstinence: Implications of an mGlu(5)-MOPr Interaction

P Zanos, P Georgiou, LR Gonzalez, S Hourani, Y Chen, I Kitchen, BL Kieffer, R Winsky-Sommerer and A Bailey

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, Vol.19(7)

01/07/2016

DOI: https://doi.org/10.1093/ijnp/pyw011

Abstract

Science & Technology

Life Sciences & Biomedicine

Clinical Neurology

Neurosciences

Pharmacology & Pharmacy

Psychiatry

Neurosciences & Neurology

Morphine

withdrawal

mu-opioid receptor

mGlu(5)R

opioids

MU-OPIOID-RECEPTOR

MGLUR5 ANTAGONIST MTEP

PROTRACTED ABSTINENCE

INDUCED REINSTATEMENT

SEEKING BEHAVIOR

METABOTROPIC GLUTAMATE-RECEPTOR-5

ANTINOCICEPTIVE TOLERANCE

CONDITIONED REWARD

DRUG-ADDICTION

MICE LACKING

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Title: Emotional Impairment and Persistent Upregulation of mGlu(5) Receptor following Morphine Abstinence: Implications of an mGlu(5)-MOPr Interaction
Creators: P Zanos
P Georgiou
LR Gonzalez
S Hourani
Y Chen
I Kitchen
BL Kieffer
R Winsky-Sommerer
A Bailey
Publication Details: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, Vol.19(7)
Publisher: OXFORD UNIV PRESS
Date published: 01/07/2016
Date submitted: 17/05/2017
Identifiers: 99513585402346
Academic Unit: University of Surrey; Faculty of Health and Medical Sciences; School of Biosciences
Language: English
Resource Type: Journal article

Emotional Impairment and Persistent Upregulation of mGlu(5) Receptor following Morphine Abstinence: Implications of an mGlu(5)-MOPr Interaction

Abstract

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