Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial

CL White; KR Twigger; L Vidal; JS De Bono; M Coffey; L Heinemann; R Morgan; A Merrick; F Errington; RG Vile; AA Melcher; HS Pandha; KJ Harrington

doi:10.1038/gt.2008.21

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Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial

Journal article

Peer reviewed

Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial

CL White, KR Twigger, L Vidal, JS De Bono, M Coffey, L Heinemann, R Morgan, A Merrick, F Errington, RG Vile, …

GENE THERAPY, Vol.15(12), pp.911-920

01/06/2008

DOI: https://doi.org/10.1038/gt.2008.21

Abstract

Science & Technology

Life Sciences & Biomedicine

Biochemistry & Molecular Biology

Biotechnology & Applied Microbiology

Genetics & Heredity

Medicine

Research & Experimental

Research & Experimental Medicine

BIOCHEMISTRY & MOLECULAR BIOLOGY

BIOTECHNOLOGY & APPLIED MICROBIOLOGY

GENETICS & HEREDITY

MEDICINE

RESEARCH & EXPERIMENTAL

immune response

reovirus

neutralizing antibody

cytokine

T-cell subset

phase I trial

HIGH-FREQUENCY

RAS

THERAPY

VIRUS

PREVALENCE

ACTIVATION

ADENOVIRUS

MUTATIONS

PATHWAY

CANCERS

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Title: Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial
Creators: CL White
KR Twigger
L Vidal
JS De Bono
M Coffey
L Heinemann
R Morgan
A Merrick
F Errington
RG Vile
AA Melcher
HS Pandha
KJ Harrington
Publication Details: GENE THERAPY, Vol.15(12), pp.911-920
Publisher: NATURE PUBLISHING GROUP
Date published: 01/06/2008
Date submitted: 17/05/2017
Identifiers: 99512519402346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial

Abstract

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