A Tyr346 -> Cys substitution in the interdomain acidic region a1 of factor VIII in an individual with factor VIII : C assay discrepancy

AD Mumford; M Laffan; J O'Donnell; JH McVey; DJD Johnson; RA Manning; G Kemball-Cook

doi:10.1046/j.1365-2141.2002.03617.x

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A Tyr346 -> Cys substitution in the interdomain acidic region a1 of factor VIII in an individual with factor VIII : C assay discrepancy

Journal article

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A Tyr346 -> Cys substitution in the interdomain acidic region a1 of factor VIII in an individual with factor VIII : C assay discrepancy

AD Mumford, M Laffan, J O'Donnell, JH McVey, DJD Johnson, RA Manning and G Kemball-Cook

BRITISH JOURNAL OF HAEMATOLOGY, Vol.118(2), pp.589-594

01/08/2002

DOI: https://doi.org/10.1046/j.1365-2141.2002.03617.x

Abstract

Science & Technology

Life Sciences & Biomedicine

Hematology

HEMATOLOGY

factor VIII

assay discrepancy

interdomain acidic region a1

factor VIII activation

FVIIIa inactivation

COAGULATION-FACTOR-VIII

HEMOPHILIA-A

IDENTIFICATION

THROMBIN

ACTIVATION

A2-SUBUNIT

MUTATIONS

SITE

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Title: A Tyr346 -> Cys substitution in the interdomain acidic region a1 of factor VIII in an individual with factor VIII : C assay discrepancy
Creators: AD Mumford
M Laffan
J O'Donnell
JH McVey
DJD Johnson
RA Manning
G Kemball-Cook
Publication Details: BRITISH JOURNAL OF HAEMATOLOGY, Vol.118(2), pp.589-594
Publisher: BLACKWELL PUBLISHING LTD
Date published: 01/08/2002
Date submitted: 17/05/2017
Identifiers: 99512511202346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

A Tyr346 -> Cys substitution in the interdomain acidic region a1 of factor VIII in an individual with factor VIII : C assay discrepancy

Abstract

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