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In Vivo Transduction of an Stx-Encoding Phage in Ruminants
Journal article   Peer reviewed

In Vivo Transduction of an Stx-Encoding Phage in Ruminants

Nancy A. Cornick, Amy F. Helgerson, Volker Mai, Jennifer M. Ritchie and David W. K. Acheson
Applied and environmental microbiology, Vol.72(7), pp.5086-5088
01/07/2006
PMID: 16820511

Abstract

Genetics and Molecular Biology
We assessed the ability of a kanamycin-marked Stx phage to move into a commensal, ovine Escherichia coli strain in the ruminant gastrointestinal tract. Transduction was detected in 19/24 sheep tested, resulting in the recovery of 47 transductants. Subtherapeutic doses of the quinolone antibiotic enrofloxacin did not increase the rate of transduction.

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