In building design, the partial load factor for self-weight of slabs is independent of the number of floors unlike variable actions, where load may be reduced for higher buildings. This simplified approach, with a typical value γ_G=1.35, has an impact on the estimated internal forces in columns and foundations, and has strong financial and material consumption implications (particularly detrimental for concrete slabs with larger significance of self-weight than alternative floor systems). For high-rise buildings, the construction sequence (only some floors propped during casting) becomes relevant on determining the internal forces. In addition, the aleatoric component of some uncertainties (as thickness of slabs) may partly compensate from floor to floor. Therefore, a constant partial load factor (independent of the number of floors) may lead to an uneven level of safety. In this paper, a semi-probabilistic analysis is performed considering modelling errors and levels of correlation between floors. As a result, tailored values of the partial load factor are determined consistently with the level of refinement used for structural analysis. A case study of a concrete building with flat slabs is finally presented showcasing the previous findings and demonstrating that considering the evolutive construction sequence allows considering lower values of γ_G≈1.20.