Use of a reporter gene assay to predict and rank the potency and efficacy of CYP3A4 inducers

W El-Sankary; GG Gibson; A Ayrton; N Plant

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Use of a reporter gene assay to predict and rank the potency and efficacy of CYP3A4 inducers

Journal article

Peer reviewed

Use of a reporter gene assay to predict and rank the potency and efficacy of CYP3A4 inducers

W El-Sankary, GG Gibson, A Ayrton and N Plant

DRUG METABOLISM AND DISPOSITION, Vol.29(11), pp.1499-1504

01/11/2001

Abstract

Science & Technology

Life Sciences & Biomedicine

Pharmacology & Pharmacy

PHARMACOLOGY & PHARMACY

COA REDUCTASE INHIBITOR

PREGNANE-X RECEPTOR

IN-VITRO

HUMAN HEPATOCYTES

PRIMARY CULTURES

TRANSCRIPTIONAL ACTIVATION

GLUCOCORTICOID RECEPTOR

CYTOCHROME-P450 ENZYMES

DRUG-INTERACTIONS

ENHANCER MODULE

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Title: Use of a reporter gene assay to predict and rank the potency and efficacy of CYP3A4 inducers
Creators: W El-Sankary
GG Gibson
A Ayrton
N Plant
Publication Details: DRUG METABOLISM AND DISPOSITION, Vol.29(11), pp.1499-1504
Publisher: AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS
Date published: 01/11/2001
Date submitted: 17/05/2017
Identifiers: 99516556702346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

Use of a reporter gene assay to predict and rank the potency and efficacy of CYP3A4 inducers

Abstract

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