Use of Human Microsomes and Deuterated Substrates: An Alternative Approach for the Identification of Novel Metabolites of Ketamine by Mass Spectrometry

SC Turfus; MC Parkin; DA Cowan; JM Halket; NW Smith; RA Braithwaite; SP Elliot; GB Steventon; AT Kicman

doi:10.1124/dmd.108.026328

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Use of Human Microsomes and Deuterated Substrates: An Alternative Approach for the Identification of Novel Metabolites of Ketamine by Mass Spectrometry

Journal article

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Use of Human Microsomes and Deuterated Substrates: An Alternative Approach for the Identification of Novel Metabolites of Ketamine by Mass Spectrometry

SC Turfus, MC Parkin, DA Cowan, JM Halket, NW Smith, RA Braithwaite, SP Elliot, GB Steventon and AT Kicman

DRUG METABOLISM AND DISPOSITION, Vol.37(8), pp.1769-1778

01/08/2009

DOI: https://doi.org/10.1124/dmd.108.026328

Abstract

Science & Technology

Life Sciences & Biomedicine

Pharmacology & Pharmacy

PHARMACOLOGY & PHARMACY

CHEMICAL-IONIZATION

N-DEMETHYLATION

VALPROIC ACID

URINE SAMPLES

HAIR ANALYSIS

NORKETAMINE

BIOTRANSFORMATION

DEHYDRONORKETAMINE

RAT

INVITRO

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Title: Use of Human Microsomes and Deuterated Substrates: An Alternative Approach for the Identification of Novel Metabolites of Ketamine by Mass Spectrometry
Creators: SC Turfus
MC Parkin
DA Cowan
JM Halket
NW Smith
RA Braithwaite
SP Elliot
GB Steventon
AT Kicman
Publication Details: DRUG METABOLISM AND DISPOSITION, Vol.37(8), pp.1769-1778
Publisher: AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS
Date published: 01/08/2009
Date submitted: 17/05/2017
Identifiers: 99512390302346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

Use of Human Microsomes and Deuterated Substrates: An Alternative Approach for the Identification of Novel Metabolites of Ketamine by Mass Spectrometry

Abstract

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