Surrey researchers Sign in
Back
Transient facial nerve paralysis (Bell's palsy) following intranasal delivery of a genetically detoxified mutant of Escherichia coli heat labile toxin.
Journal article   Peer reviewed

Transient facial nerve paralysis (Bell's palsy) following intranasal delivery of a genetically detoxified mutant of Escherichia coli heat labile toxin.

DJ Lewis, Z Huo, S Barnett, I Kromann, R Giemza, E Galiza, M Woodrow, B Thierry-Carstensen, P Andersen and D Novicki
PLoS One, Vol.4(9), pp.e6999-?
2009
DOI: https://doi.org/10.1371/journal.pone.0006999

Abstract

AIDS Vaccines Adult Axons Bacterial Toxins Bell Palsy Enterotoxins Escherichia coli Escherichia coli Proteins Female Gangliosides Humans Inflammation Male Mutation Protein Binding Tuberculosis Vaccines Vaccines Inactivated
An association was previously established between facial nerve paralysis (Bell's palsy) and intranasal administration of an inactivated influenza virosome vaccine containing an enzymatically active Escherichia coli Heat Labile Toxin (LT) adjuvant. The individual component(s) responsible for paralysis were not identified, and the vaccine was withdrawn.

Metrics

35 Record Views
231 Times Cited - Web of Science

Details

Usage Policy

Usage details for all content viewed and downloaded in this site are shared with IRUS-UK (Institutional Repository Usage Statistics UK). Cookies are used to remember your decision. Click Accept to accept usage details sharing and the cookies.

Learn more