Transcriptional regulation of the human pregnane-X receptor

GG Gibson; A Phillips; S Aouabdi; K Plant; N Plant

doi:10.1080/03602530600569810

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Transcriptional regulation of the human pregnane-X receptor

Journal article

Peer reviewed

Transcriptional regulation of the human pregnane-X receptor

GG Gibson, A Phillips, S Aouabdi, K Plant and N Plant

DRUG METABOLISM REVIEWS, Vol.38(1-2), pp.31-49

01/01/2006

DOI: https://doi.org/10.1080/03602530600569810

Abstract

Science & Technology

Life Sciences & Biomedicine

Pharmacology & Pharmacy

PHARMACOLOGY & PHARMACY

pregnane-X receptor

transcriptional regulation

induction

nuclear receptors

PXR promoter

PXR regulation

PPAR alpha

in silica promoter analysis

CONSTITUTIVE ANDROSTANE RECEPTOR

ORPHAN NUCLEAR RECEPTORS

LIGAND-BINDING DOMAIN

CYP3A GENE-EXPRESSION

HUMAN HEPATOCYTES

GLUCOCORTICOID RECEPTOR

MOLECULAR-MECHANISMS

DEPENDENT INDUCTION

ACTIVATED-RECEPTOR

MEDIATED INDUCTION

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Title: Transcriptional regulation of the human pregnane-X receptor
Creators: GG Gibson
A Phillips
S Aouabdi
K Plant
N Plant
Publication Details: DRUG METABOLISM REVIEWS, Vol.38(1-2), pp.31-49
Publisher: INFORMA HEALTHCARE
Date published: 01/01/2006
Date submitted: 17/05/2017
Identifiers: 99516106602346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

Transcriptional regulation of the human pregnane-X receptor

Abstract

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