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The use of genome scale metabolic flux variability analysis for process feed formulation based on an investigation of the effects of the zwf mutation on antibiotic production in Streptomyces coelicolor
Journal article

The use of genome scale metabolic flux variability analysis for process feed formulation based on an investigation of the effects of the zwf mutation on antibiotic production in Streptomyces coelicolor

ME Bushell, SIP Sequeira, C Khannapho, H Zhao, KF Chater, MJ Butler, AM Kierzek and CA Avignone-Rossa
ENZYME AND MICROBIAL TECHNOLOGY, Vol.39(6), pp.1347-1353
03/10/2006

Abstract

Science & Technology Life Sciences & Biomedicine Biotechnology & Applied Microbiology flux variability analysis actinorbodin streptomyces antibiotic production antibiotic biosynthesis Streptomyces coelicolor ESCHERICHIA-COLI BALANCE ANALYSIS MODELS A3(2) MANIPULATION CLAVULIGERUS PHYSIOLOGY NETWORKS SEQUENCE VECTORS
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