The nicotinic alpha 4 beta 2 receptor selective agonist, TC-2559, increases dopamine neuronal activity in the ventral tegmental area of rat midbrain slices

Y Chen; TJW Sharples; KG Phillips; G Benedetti; LM Broad; R Zwart; E Sher

doi:10.1016/S0028-3908(03)00189-8

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The nicotinic alpha 4 beta 2 receptor selective agonist, TC-2559, increases dopamine neuronal activity in the ventral tegmental area of rat midbrain slices

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The nicotinic alpha 4 beta 2 receptor selective agonist, TC-2559, increases dopamine neuronal activity in the ventral tegmental area of rat midbrain slices

Y Chen, TJW Sharples, KG Phillips, G Benedetti, LM Broad, R Zwart and E Sher

NEUROPHARMACOLOGY, Vol.45(3), pp.334-344

01/09/2003

DOI: https://doi.org/10.1016/S0028-3908(03)00189-8

Abstract

Science & Technology

Life Sciences & Biomedicine

Neurosciences

Pharmacology & Pharmacy

Neurosciences & Neurology

NEUROSCIENCES

PHARMACOLOGY & PHARMACY

alpha 4 beta 2 nicotinic receptors

TC-2559

ventral tegmental area (VTA)

dopaminergic neurons

partial agonist

neuronal firing

rat midbrain slice

Xenopus oocyte

FLIPR

voltage clamp

firing frequency

ACETYLCHOLINE-RECEPTORS

PHYSIOLOGICAL DIVERSITY

BETA-2 SUBUNIT

MUTANT MICE

BRAIN

DESENSITIZATION

EXPRESSION

MODULATION

INVITRO

INPUTS

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Title: The nicotinic alpha 4 beta 2 receptor selective agonist, TC-2559, increases dopamine neuronal activity in the ventral tegmental area of rat midbrain slices
Creators: Y Chen
TJW Sharples
KG Phillips
G Benedetti
LM Broad
R Zwart
E Sher
Publication Details: NEUROPHARMACOLOGY, Vol.45(3), pp.334-344
Publisher: PERGAMON-ELSEVIER SCIENCE LTD
Date published: 01/09/2003
Date submitted: 12/03/2012
Identifiers: 99513232502346
Academic Unit: School of Biosciences
Language: English
Resource Type: Journal article

The nicotinic alpha 4 beta 2 receptor selective agonist, TC-2559, increases dopamine neuronal activity in the ventral tegmental area of rat midbrain slices

Abstract

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