The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer

AFA Razis; R Iori; C Ioannides

doi:10.1002/ijc.25620

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Journal article

The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer

AFA Razis, R Iori and C Ioannides

INTERNATIONAL JOURNAL OF CANCER, Vol.128(12), pp.2775-2782

15/06/2011

DOI: https://doi.org/10.1002/ijc.25620

Abstract

Science & Technology

Life Sciences & Biomedicine

Oncology

ONCOLOGY

sulforaphane

isothiocyanates

glucosinolates

chemoprevention

chirality

PRECISION-CUT LIVER

ALIPHATIC ISOTHIOCYANATES ERUCIN

PHENETHYL ISOTHIOCYANATE

CYTOCHROMES P450

PHARMACOKINETIC BEHAVIOR

ADDUCT FORMATION

DYNAMIC ORGAN

SLICES

MODULATION

INDUCTION

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Title: The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer
Creators: AFA Razis
R Iori
C Ioannides
Publication Details: INTERNATIONAL JOURNAL OF CANCER, Vol.128(12), pp.2775-2782
Publisher: WILEY-BLACKWELL
Date published: 15/06/2011
Date submitted: 01/03/2012
Identifiers: 99514775902346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer

Abstract

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