The balance of apoptotic and necrotic cell death in Mycobacterium tuberculosis infected macrophages is not dependent on bacterial virulence.

RE Butler; P Brodin; J Jang; MS Jang; BD Robertson; B Gicquel; GR Stewart

doi:10.1371/journal.pone.0047573

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The balance of apoptotic and necrotic cell death in Mycobacterium tuberculosis infected macrophages is not dependent on bacterial virulence.

Journal article

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The balance of apoptotic and necrotic cell death in Mycobacterium tuberculosis infected macrophages is not dependent on bacterial virulence.

RE Butler, P Brodin, J Jang, MS Jang, BD Robertson, B Gicquel and GR Stewart

PLoS One, Vol.7(10), pp.e47573-?

2012

DOI: https://doi.org/10.1371/journal.pone.0047573

Abstract

An important mechanism of Mycobacterium tuberculosis pathogenesis is the ability to control cell death pathways in infected macrophages: apoptotic cell death is bactericidal, whereas necrotic cell death may facilitate bacterial dissemination and transmission.

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Title: The balance of apoptotic and necrotic cell death in Mycobacterium tuberculosis infected macrophages is not dependent on bacterial virulence.
Creators: RE Butler
P Brodin
J Jang
MS Jang
BD Robertson
B Gicquel
GR Stewart
Publication Details: PLoS One, Vol.7(10), pp.e47573-?
Publisher: Public Library of Science
Date published: 2012
Date submitted: 17/01/2013
Identifiers: 99511724702346
Academic Unit: School of Biosciences
Language: English
Resource Type: Journal article

The balance of apoptotic and necrotic cell death in Mycobacterium tuberculosis infected macrophages is not dependent on bacterial virulence.

Abstract

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