Quantitative structure-activity relationships in a series of endogenous and synthetic steroids exhibiting induction of CYP3A activity and hepatomegaly associated with increased DNA synthesis

DFV Lewis; C Ioannides; DV Parke; R Schulte-Hermann

doi:10.1016/S0960-0760(00)00121-7

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Journal article

Quantitative structure-activity relationships in a series of endogenous and synthetic steroids exhibiting induction of CYP3A activity and hepatomegaly associated with increased DNA synthesis

DFV Lewis, C Ioannides, DV Parke and R Schulte-Hermann

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, Vol.74(4), pp.179-185

15/11/2000

DOI: https://doi.org/10.1016/S0960-0760(00)00121-7

Abstract

Science & Technology

Life Sciences & Biomedicine

Biochemistry & Molecular Biology

Endocrinology & Metabolism

BIOCHEMISTRY & MOLECULAR BIOLOGY

ENDOCRINOLOGY & METABOLISM

QSAR

CYP3A

ethylmorphine N-demethylase

RAT-LIVER

ESTROGEN-RECEPTOR

MICROSOMAL P450S

MOLECULAR-BASIS

EXPRESSION

LIGAND

GROWTH

ACID

MONOOXYGENASES

SUBFAMILY

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Title: Quantitative structure-activity relationships in a series of endogenous and synthetic steroids exhibiting induction of CYP3A activity and hepatomegaly associated with increased DNA synthesis
Creators: DFV Lewis
C Ioannides
DV Parke
R Schulte-Hermann
Publication Details: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, Vol.74(4), pp.179-185
Publisher: PERGAMON-ELSEVIER SCIENCE LTD
Date published: 15/11/2000
Date submitted: 17/05/2017
Identifiers: 99516451802346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

Quantitative structure-activity relationships in a series of endogenous and synthetic steroids exhibiting induction of CYP3A activity and hepatomegaly associated with increased DNA synthesis

Abstract

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