Quantitative structure-activity relationships (QSARs) in CYP3A4 inhibitors: The importance of lipophilic character and hydrogen bonding

DFV Lewis; BG Lake; M Dickns

doi:10.1080/14756360500532747

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Quantitative structure-activity relationships (QSARs) in CYP3A4 inhibitors: The importance of lipophilic character and hydrogen bonding

Journal article

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Quantitative structure-activity relationships (QSARs) in CYP3A4 inhibitors: The importance of lipophilic character and hydrogen bonding

DFV Lewis, BG Lake and M Dickns

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, Vol.21(2), pp.127-132

01/04/2006

DOI: https://doi.org/10.1080/14756360500532747

Abstract

Science & Technology

Life Sciences & Biomedicine

Biochemistry & Molecular Biology

Chemistry

Medicinal

Pharmacology & Pharmacy

BIOCHEMISTRY & MOLECULAR BIOLOGY

CHEMISTRY

MEDICINAL

CYP3A4

inhibition

partition coefficient

statins

QSAR

HUMAN CYTOCHROMES P450

DRUG-METABOLISM

IN-VITRO

ENZYMES

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Title: Quantitative structure-activity relationships (QSARs) in CYP3A4 inhibitors: The importance of lipophilic character and hydrogen bonding
Creators: DFV Lewis
BG Lake
M Dickns
Publication Details: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, Vol.21(2), pp.127-132
Publisher: TAYLOR & FRANCIS LTD
Date published: 01/04/2006
Date submitted: 17/05/2017
Identifiers: 99511668502346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

Quantitative structure-activity relationships (QSARs) in CYP3A4 inhibitors: The importance of lipophilic character and hydrogen bonding

Abstract

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