O-6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo

J Klapacz; LB Meira; DG Luchetti; JA Calvo; RT Bronson; W Edelmann; LD Samson

doi:10.1073/pnas.0811991106

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O-6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo

Journal article

Peer reviewed

O-6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo

J Klapacz, LB Meira, DG Luchetti, JA Calvo, RT Bronson, W Edelmann and LD Samson

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol.106(2), pp.576-581

13/01/2009

DOI: https://doi.org/10.1073/pnas.0811991106

Abstract

Science & Technology

Multidisciplinary Sciences

Science & Technology - Other Topics

MULTIDISCIPLINARY SCIENCES

alkylation resistance

apoptosis

DNA alkylation

Mgmt

N-methyl-N '-nitrosourea (MNU)

CHEMOTHERAPEUTIC ALKYLATING-AGENTS

SACCHAROMYCES-CEREVISIAE EXO1

ESCHERICHIA-COLI DNA

REPAIR METHYLTRANSFERASE

HOMOLOGOUS RECOMBINATION

CANCER SUSCEPTIBILITY

MUTL-ALPHA

MICE

GENE

MUTATION

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Title: O-6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo
Creators: J Klapacz
LB Meira
DG Luchetti
JA Calvo
RT Bronson
W Edelmann
LD Samson
Publication Details: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol.106(2), pp.576-581
Publisher: NATL ACAD SCIENCES
Date published: 13/01/2009
Date submitted: 09/11/2011
Identifiers: 99511339502346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

O-6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo

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