Neuroblasts contribute to oligodendrocytes generation upon demyelination in the adult mouse brain

Bilal El Waly; Claire Bertet; Mathilde Paris; Marie Falque; Pierre Milpied; Karine Magalon; Myriam Cayre; Pascale Durbec; Vikrant Singh

doi:10.1016/j.isci.2022.105102

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Neuroblasts contribute to oligodendrocytes generation upon demyelination in the adult mouse brain

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Neuroblasts contribute to oligodendrocytes generation upon demyelination in the adult mouse brain

Bilal El Waly, Claire Bertet, Mathilde Paris, Marie Falque, Pierre Milpied, Karine Magalon, Myriam Cayre, Pascale Durbec and Vikrant Singh

iScience, Vol.25(10), p.105102

21/10/2022

DOI: https://doi.org/10.1016/j.isci.2022.105102

Abstract

Life Sciences

Highlights NB can contribute to myelin repair by converting into oligodendrocytes NB fate conversion occurs gradually, through formation of an intermediate cell type NB fate conversion does not involve reversion toward a pluripotent state NB fate conversion seems to involve EMT-related mechanisms and metabolic changes

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Title: Neuroblasts contribute to oligodendrocytes generation upon demyelination in the adult mouse brain
Creators: Bilal El Waly - Institut de Biologie du Développement de Marseille
Claire Bertet - Institut de Biologie du Développement de Marseille
Mathilde Paris - Institut de Biologie du Développement de Marseille
Marie Falque - Institut de Biologie du Développement de Marseille
Pierre Milpied - Centre d’Immunologie de Marseille-Luminy
Karine Magalon - Institut de Biologie du Développement de Marseille
Myriam Cayre - Institut de Biologie du Développement de Marseille
Pascale Durbec - Institut de Biologie du Développement de Marseille
Vikrant Singh - Department of Electrical and Electronic Engineering
Publication Details: iScience, Vol.25(10), p.105102
Publisher: Elsevier
First online publication date: 13/09/2022
Publication Date: 21/10/2022
Date accepted for publication: 05/09/2022
Identifiers: 99783515102346
Academic Unit: School of Computer Science and Electronic Engineering
Language: English
Resource Type: Journal article

Neuroblasts contribute to oligodendrocytes generation upon demyelination in the adult mouse brain

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