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NR4A2 genetic variation in sporadic Parkinson's disease: a genewide approach.
Journal article   Peer reviewed

NR4A2 genetic variation in sporadic Parkinson's disease: a genewide approach.

DG Healy, PM Abou-Sleiman, KR Ahmadi, S Gandhi, MM Muqit, KP Bhatia, NP Quinn, AJ Lees, JL Holton, T Revesz, …
Mov Disord, Vol.21(11), pp.1960-1963
11/2006
DOI: https://doi.org/10.1002/mds.21018

Abstract

Case-Control Studies Chi-Square Distribution DNA-Binding Proteins Female Gene Frequency Genetic Predisposition to Disease Genetic Variation Genotype Humans Male Middle Aged Nuclear Receptor Subfamily 4 Group A Member 2 Parkinson Disease Transcription Factors
The NR4A2 gene, which may cause autosomal dominant Parkinson's disease (PD), has also been reported to be a susceptibility factor for sporadic PD. Here, we use a haplotype-tagging approach in 802 PD patients and 784 controls and demonstrate that common genetic variation, including NR4A2 haplotypes, does not influence the risk of PD in the Caucasian population.
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http://www.ncbi.nlm.nih.gov/pubmed/16977628View
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