Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses

RP Beyer; RC Fry; MR Lasarev; LA McConnachie; LB Meira; VS Palmer; CL Powell; PK Ross; TK Bammler; BU Bradford; AB Cranson; ML Cunningham; RD Fannin; GM Higgins; P Hurban; RJ Kayton; KF Kerr; O Kosyk; EK Lobenhofer; SO Sieber; PA Vliet; BK Weis; R Wolfinger; CG Woods; JH Freedman; E Linney; WK Kaufmann; TJ Kavanagh; RS Paules; I Rusyn; LD Samson; PS Spencer; W Suk; RJ Tennant; H Zarbl

doi:10.1093/toxsci/kfm150

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Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses

Journal article

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Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses

RP Beyer, RC Fry, MR Lasarev, LA McConnachie, LB Meira, VS Palmer, CL Powell, PK Ross, TK Bammler, BU Bradford, …

TOXICOLOGICAL SCIENCES, Vol.99(1), pp.326-337

01/09/2007

DOI: https://doi.org/10.1093/toxsci/kfm150

Abstract

Science & Technology

Life Sciences & Biomedicine

Toxicology

TOXICOLOGY

liver injury

toxicogenomics

phenotypic anchoring

GENE-EXPRESSION ANALYSIS

GLUTATHIONE DEPLETION

MICROARRAY DATA

MOUSE-LIVER

RAT-LIVER

IN-VIVO

TOXICOGENOMICS

INHIBITION

PROFILES

STRESS

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Title: Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses
Creators: RP Beyer
RC Fry
MR Lasarev
LA McConnachie
LB Meira
VS Palmer
CL Powell
PK Ross
TK Bammler
BU Bradford
AB Cranson
ML Cunningham
RD Fannin
GM Higgins
P Hurban
RJ Kayton
KF Kerr
O Kosyk
EK Lobenhofer
SO Sieber
PA Vliet
BK Weis
R Wolfinger
CG Woods
JH Freedman
E Linney
WK Kaufmann
TJ Kavanagh
RS Paules
I Rusyn
LD Samson
PS Spencer
W Suk
RJ Tennant
H Zarbl
Publication Details: TOXICOLOGICAL SCIENCES, Vol.99(1), pp.326-337
Publisher: OXFORD UNIV PRESS
Date published: 01/09/2007
Date submitted: 17/05/2017
Identifiers: 99514273702346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses

Abstract

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