Mixed chelate copper complex, Casiopeina IIgly (R), binds and degrades nucleic acids: A mechanism of cytotoxicity

A Rivero-Muller; A De Vizcaya-Ruiz; N Plant; L Ruiz; M Dobrota

doi:10.1016/j.cbi.2006.12.002

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Journal article

Mixed chelate copper complex, Casiopeina IIgly (R), binds and degrades nucleic acids: A mechanism of cytotoxicity

A Rivero-Muller, A De Vizcaya-Ruiz, N Plant, L Ruiz and M Dobrota

CHEMICO-BIOLOGICAL INTERACTIONS, Vol.165(3), pp.189-199

20/02/2007

DOI: https://doi.org/10.1016/j.cbi.2006.12.002

Abstract

Science & Technology

Life Sciences & Biomedicine

Biochemistry & Molecular Biology

Pharmacology & Pharmacy

Toxicology

BIOCHEMISTRY & MOLECULAR BIOLOGY

PHARMACOLOGY & PHARMACY

TOXICOLOGY

mixed chelate

copper complexes

casiopeinas

nucleic acid

redox reaction

ROS

8-oxodG

DNA-DAMAGE

CHEMICAL NUCLEASES

CELLS

APOPTOSIS

RADICALS

CLEAVAGE

1

10-PHENANTHROLINE

GENERATION

RADIATION

PEROXIDE

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Title: Mixed chelate copper complex, Casiopeina IIgly (R), binds and degrades nucleic acids: A mechanism of cytotoxicity
Creators: A Rivero-Muller
A De Vizcaya-Ruiz
N Plant
L Ruiz
M Dobrota
Publication Details: CHEMICO-BIOLOGICAL INTERACTIONS, Vol.165(3), pp.189-199
Publisher: ELSEVIER IRELAND LTD
Date published: 20/02/2007
Date submitted: 17/05/2017
Identifiers: 99516063302346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

Mixed chelate copper complex, Casiopeina IIgly (R), binds and degrades nucleic acids: A mechanism of cytotoxicity

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