MOLECULAR MODELING OF CYTOCHROME CYP1A1 - A PUTATIVE ACCESS CHANNEL EXPLAINS DIFFERENCES IN INDUCTION POTENCY BETWEEN THE ISOMERS BENZO(A)PYRENE AND BENZO(E)PYRENE, AND 2-ACETYLAMINOFLUORENE AND 4-ACETYLAMINOFLUORENE

DFV LEWIS; C IOANNIDES; DV PARKE

doi:10.1016/0378-4274(94)90110-4

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MOLECULAR MODELING OF CYTOCHROME CYP1A1 - A PUTATIVE ACCESS CHANNEL EXPLAINS DIFFERENCES IN INDUCTION POTENCY BETWEEN THE ISOMERS BENZO(A)PYRENE AND BENZO(E)PYRENE, AND 2-ACETYLAMINOFLUORENE AND 4-ACETYLAMINOFLUORENE

DFV LEWIS, C IOANNIDES and DV PARKE

TOXICOLOGY LETTERS, Vol.71(3), pp.235-243

01/05/1994

DOI: https://doi.org/10.1016/0378-4274(94)90110-4

Abstract

Science & Technology

Life Sciences & Biomedicine

Toxicology

TOXICOLOGY

CYTOCHROMES P450

MIXED-FUNCTION OXIDASES

ENZYME INDUCTION

ACETYLAMINOFLUORENE

BENZOPYRENE

MOLECULAR MODELING

POLYCYCLIC AROMATIC-HYDROCARBONS

PROTEINS

ENZYMES

FAMILY

CARCINOGENESIS

BIOACTIVATION

OMEPRAZOLE

TOXICITY

CANCER

SITE

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Title: MOLECULAR MODELING OF CYTOCHROME CYP1A1 - A PUTATIVE ACCESS CHANNEL EXPLAINS DIFFERENCES IN INDUCTION POTENCY BETWEEN THE ISOMERS BENZO(A)PYRENE AND BENZO(E)PYRENE, AND 2-ACETYLAMINOFLUORENE AND 4-ACETYLAMINOFLUORENE
Creators: DFV LEWIS
C IOANNIDES
DV PARKE
Publication Details: TOXICOLOGY LETTERS, Vol.71(3), pp.235-243
Publisher: ELSEVIER SCI IRELAND LTD
Date published: 01/05/1994
Date submitted: 17/05/2017
Identifiers: 99511798002346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

MOLECULAR MODELING OF CYTOCHROME CYP1A1 - A PUTATIVE ACCESS CHANNEL EXPLAINS DIFFERENCES IN INDUCTION POTENCY BETWEEN THE ISOMERS BENZO(A)PYRENE AND BENZO(E)PYRENE, AND 2-ACETYLAMINOFLUORENE AND 4-ACETYLAMINOFLUORENE

Abstract

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