Lipophilicity relationships in inhibitors of CYP2C9 and CYP2C19 enzymes

DFV Lewis; BG Lake; Y Ito; M Dickins

doi:10.1080/14756360600703313

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Lipophilicity relationships in inhibitors of CYP2C9 and CYP2C19 enzymes

Journal article

Peer reviewed

Lipophilicity relationships in inhibitors of CYP2C9 and CYP2C19 enzymes

DFV Lewis, BG Lake, Y Ito and M Dickins

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, Vol.21(4), pp.385-389

01/08/2006

DOI: https://doi.org/10.1080/14756360600703313

Abstract

Science & Technology

Life Sciences & Biomedicine

Biochemistry & Molecular Biology

Chemistry

Medicinal

Pharmacology & Pharmacy

BIOCHEMISTRY & MOLECULAR BIOLOGY

CHEMISTRY

MEDICINAL

cYP2C9

CYP2C19

inhibition

substrates

liphophilicity

MAMMALIAN CYTOCHROME P4502C5

HUMAN LIVER-MICROSOMES

SUBSTRATE-BINDING

DRUG-METABOLISM

ANGSTROM RESOLUTION

IN-VITRO

HYDROXYLASE

OMEPRAZOLE

VALUES

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Title: Lipophilicity relationships in inhibitors of CYP2C9 and CYP2C19 enzymes
Creators: DFV Lewis
BG Lake
Y Ito
M Dickins
Publication Details: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, Vol.21(4), pp.385-389
Publisher: TAYLOR & FRANCIS LTD
Date published: 01/08/2006
Date submitted: 17/05/2017
Identifiers: 99511312902346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

Lipophilicity relationships in inhibitors of CYP2C9 and CYP2C19 enzymes

Abstract

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