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Kinase joins the chaperone club: Androgen-regulated kinome reveals choline kinase alpha as a potential drug target in prostate cancer
Journal article

Kinase joins the chaperone club: Androgen-regulated kinome reveals choline kinase alpha as a potential drug target in prostate cancer

Mohammad Asim, Charlie E. Massie and David E. Neal
Molecular & cellular oncology, Vol.3(3), p.e1140262
03/05/2016
DOI: https://doi.org/10.1080/23723556.2016.1140262
PMID: 27314091

Abstract

Androgen Receptor chaperones prostate cancer therapeutic target
To identify clinically relevant downstream effectors of androgen signaling, the androgen-regulated kinome was defined in prostate cancer (PCa). Within this study, choline kinase α (CHKA) was identified as an androgen receptor chaperone that is both a biomarker of progression and a potential therapeutic target for PCa.
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https://doi.org/10.1080/23723556.2016.1140262View
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