In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-O Delta N89 beta-catenin system

T Jarde; RJ Evans; KL McQuillan; L Parry; GJ Feng; B Alvares; AR Clarke; TC Dale

doi:10.1038/onc.2012.103

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In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-O Delta N89 beta-catenin system

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In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-O Delta N89 beta-catenin system

T Jarde, RJ Evans, KL McQuillan, L Parry, GJ Feng, B Alvares, AR Clarke and TC Dale

ONCOGENE, Vol.32(7), pp.883-893

14/02/2013

DOI: https://doi.org/10.1038/onc.2012.103

Abstract

Science & Technology

Life Sciences & Biomedicine

Biochemistry & Molecular Biology

Oncology

Cell Biology

Genetics & Heredity

BIOCHEMISTRY & MOLECULAR BIOLOGY

CELL BIOLOGY

GENETICS & HEREDITY

ONCOLOGY

Wnt pathway

reversal

colorectal cancer

crypt culture

organoids

SMALL-MOLECULE INHIBITORS

BETA-CATENIN

STEM-CELLS

WNT/BETA-CATENIN

TRANSGENIC MICE

SMALL-INTESTINE

CANCER

DIFFERENTIATION

EXPRESSION

APOPTOSIS

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Title: In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-O Delta N89 beta-catenin system
Creators: T Jarde
RJ Evans
KL McQuillan
L Parry
GJ Feng
B Alvares
AR Clarke
TC Dale
Publication Details: ONCOGENE, Vol.32(7), pp.883-893
Publisher: NATURE PUBLISHING GROUP
Date published: 14/02/2013
Date submitted: 17/05/2017
Identifiers: 99515330302346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-O Delta N89 beta-catenin system

Abstract

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