Human cytochromes P450 in the metabolism of drugs: new molecular models of enzyme-substrate interactions

DFV Lewis; Y Ito

doi:10.1517/17425250802352412

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Human cytochromes P450 in the metabolism of drugs: new molecular models of enzyme-substrate interactions

Journal article

Peer reviewed

Human cytochromes P450 in the metabolism of drugs: new molecular models of enzyme-substrate interactions

DFV Lewis and Y Ito

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, Vol.4(9), pp.1181-1186

01/09/2008

DOI: https://doi.org/10.1517/17425250802352412

Abstract

Science & Technology

Life Sciences & Biomedicine

Biochemistry & Molecular Biology

Pharmacology & Pharmacy

BIOCHEMISTRY & MOLECULAR BIOLOGY

PHARMACOLOGY & PHARMACY

cytochromes P450

drug metabolism

enzyme structures

molecular modelling

CRYSTAL-STRUCTURES

BINDING-AFFINITY

IN-VITRO

RESOLUTION

2D6

INHIBITORS

CLEARANCE

CYP2

SITE

3A4

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Title: Human cytochromes P450 in the metabolism of drugs: new molecular models of enzyme-substrate interactions
Creators: DFV Lewis
Y Ito
Publication Details: EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, Vol.4(9), pp.1181-1186
Publisher: INFORMA HEALTHCARE
Date published: 01/09/2008
Date submitted: 17/05/2017
Identifiers: 99515649702346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

Human cytochromes P450 in the metabolism of drugs: new molecular models of enzyme-substrate interactions

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