Human P450s involved in drug metabolism and the use of structural modelling for understanding substrate selectivity and binding affinity

DFV Lewis; Y Ito

doi:10.1080/00498250903000255

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Journal article

Human P450s involved in drug metabolism and the use of structural modelling for understanding substrate selectivity and binding affinity

DFV Lewis and Y Ito

XENOBIOTICA, Vol.39(8), pp.625-635

01/01/2009

DOI: https://doi.org/10.1080/00498250903000255

Abstract

Science & Technology

Life Sciences & Biomedicine

Pharmacology & Pharmacy

Toxicology

PHARMACOLOGY & PHARMACY

TOXICOLOGY

Human cytochrome P450s

substrate selectivity

binding affinity

HUMAN CYTOCHROMES P450

CHEMICAL TOXICOLOGY

ANGSTROM RESOLUTION

AUTOMATED DOCKING

CRYSTAL-STRUCTURE

FAMILY ENZYMES

K-M

LIPOPHILICITY

QSARS

3A4

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Title: Human P450s involved in drug metabolism and the use of structural modelling for understanding substrate selectivity and binding affinity
Creators: DFV Lewis
Y Ito
Publication Details: XENOBIOTICA, Vol.39(8), pp.625-635
Publisher: TAYLOR & FRANCIS LTD
Date published: 01/01/2009
Date submitted: 17/05/2017
Identifiers: 99515662202346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

Human P450s involved in drug metabolism and the use of structural modelling for understanding substrate selectivity and binding affinity

Abstract

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