Human CYPs involved in drug metabolism: structures, substrates and binding affinities

DFV Lewis; Y Ito

doi:10.1517/17425251003674380

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Human CYPs involved in drug metabolism: structures, substrates and binding affinities

Journal article

Peer reviewed

Human CYPs involved in drug metabolism: structures, substrates and binding affinities

DFV Lewis and Y Ito

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, Vol.6(6), pp.661-674

01/06/2010

DOI: https://doi.org/10.1517/17425251003674380

Abstract

Science & Technology

Life Sciences & Biomedicine

Biochemistry & Molecular Biology

Pharmacology & Pharmacy

BIOCHEMISTRY & MOLECULAR BIOLOGY

PHARMACOLOGY & PHARMACY

CYP

drug metabolism

molecular modelling

quantitative structure-activity relationships

substrate binding

HUMAN CYTOCHROMES P450

COMPOUND LIPOPHILICITY

CHEMICAL TOXICOLOGY

K-M

ENZYMES

INHIBITORS

HOMOLOGY

MODELS

QSAR

3A4

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Title: Human CYPs involved in drug metabolism: structures, substrates and binding affinities
Creators: DFV Lewis
Y Ito
Publication Details: EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, Vol.6(6), pp.661-674
Publisher: INFORMA HEALTHCARE
Date published: 01/06/2010
Date submitted: 17/05/2017
Identifiers: 99512170202346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

Human CYPs involved in drug metabolism: structures, substrates and binding affinities

Abstract

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