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Growth limiting substrate affects antibiotic production and associated metabolic fluxes in Streptomyces clavuligerus
Journal article   Peer reviewed

Growth limiting substrate affects antibiotic production and associated metabolic fluxes in Streptomyces clavuligerus

S Kirk, CA Avignone-Rossa and ME Bushell
BIOTECHNOLOGY LETTERS, Vol.22(22), pp.1803-1809
01/11/2000

Abstract

Science & Technology Life Sciences & Biomedicine Biotechnology & Applied Microbiology BIOTECHNOLOGY & APPLIED MICROBIOLOGY chemostat culture clavulanic acid fermentation technology metabolic flux analysis FED-BATCH CULTURE CLAVULANIC ACID SACCHAROPOLYSPORA-ERYTHRAEA ERYTHROMYCIN PRODUCTION ESCHERICHIA-COLI BIOSYNTHESIS HYGROSCOPICUS PHYSIOLOGY PATHWAYS PROTEIN
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