Evidence for a shift to anaerobic metabolism in adipose tissue in efavirenz-containing regimens for HIV with different nucleoside backbones.

KC McGee; M Shahmanesh; M Boothby; P Nightingale; LL Gathercole; G Tripathi; AL Harte; F Shojaee-Moradie; AM Umpleby; S Das; NM Al-Daghri; PG McTernan; JW Tomlinson

doi:10.3851/IMP2017

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Evidence for a shift to anaerobic metabolism in adipose tissue in efavirenz-containing regimens for HIV with different nucleoside backbones.

KC McGee, M Shahmanesh, M Boothby, P Nightingale, LL Gathercole, G Tripathi, AL Harte, F Shojaee-Moradie, AM Umpleby, S Das, …

Antivir Ther, Vol.17(3), pp.495-507

2012

DOI: https://doi.org/10.3851/IMP2017

Abstract

Antiretroviral (ARV) treatment has been associated with abnormalities in lipid and mitochondrial metabolism. We compared patterns of gene expression in the subcutaneous adipose tissue (SAT) of HIV-positive subjects before and after 18-24 months of ARV therapy with HIV-negative controls.

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Title: Evidence for a shift to anaerobic metabolism in adipose tissue in efavirenz-containing regimens for HIV with different nucleoside backbones.
Creators: KC McGee
M Shahmanesh
M Boothby
P Nightingale
LL Gathercole
G Tripathi
AL Harte
F Shojaee-Moradie
AM Umpleby
S Das
NM Al-Daghri
PG McTernan
JW Tomlinson
Publication Details: Antivir Ther, Vol.17(3), pp.495-507
Date published: 2012
Date submitted: 17/05/2017
Identifiers: 99513035502346
Academic Unit: University of Surrey; School of Biosciences
Language: English
Resource Type: Journal article

Evidence for a shift to anaerobic metabolism in adipose tissue in efavirenz-containing regimens for HIV with different nucleoside backbones.

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