Evaluation of the toxicological relevance of CYP3A4 induction

NJ Plant; GG Gibson

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Evaluation of the toxicological relevance of CYP3A4 induction

Journal article

Peer reviewed

Evaluation of the toxicological relevance of CYP3A4 induction

NJ Plant and GG Gibson

CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT, Vol.6(1), pp.50-56

01/01/2003

Abstract

Science & Technology

Life Sciences & Biomedicine

Pharmacology & Pharmacy

PHARMACOLOGY & PHARMACY

CYP3A4

drug-drug interaction

PXR

transcriptional activation

PREGNANE-X-RECEPTOR

REVERSE-TRANSCRIPTASE INHIBITOR

REPORTER GENE ASSAY

PHARMACOKINETIC INTERACTIONS

NUCLEAR RECEPTOR

DRUG-METABOLISM

EXPRESSION

EFAVIRENZ

CYTOCHROME-P450

ACTIVATION

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Title: Evaluation of the toxicological relevance of CYP3A4 induction
Creators: NJ Plant
GG Gibson
Publication Details: CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT, Vol.6(1), pp.50-56
Publisher: CURRENT DRUGS LTD
Date published: 01/01/2003
Date submitted: 17/05/2017
Identifiers: 99516390702346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

Evaluation of the toxicological relevance of CYP3A4 induction

Abstract

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