Evaluation of the activity of a novel metabotropic glutamate receptor antagonist (+/-)-2-amino-2-(3-cis and trans-carboxycyclobutyl-3-(9-thioxanthyl acid) in the in vitro neonatal spinal cord and in an in vivo pain model

Y Chen; G Bacon; E Sher; BP Clark; MJ Kallman; RA Wright; BG Johnson; DD Schoepp; AE Kingston

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Evaluation of the activity of a novel metabotropic glutamate receptor antagonist (+/-)-2-amino-2-(3-cis and trans-carboxycyclobutyl-3-(9-thioxanthyl acid) in the in vitro neonatal spinal cord and in an in vivo pain model

Y Chen, G Bacon, E Sher, BP Clark, MJ Kallman, RA Wright, BG Johnson, DD Schoepp and AE Kingston

NEUROSCIENCE, Vol.95(3), pp.787-793

01/01/2000

Abstract

Science & Technology

Life Sciences & Biomedicine

Neurosciences

Neurosciences & Neurology

NEUROSCIENCES

group I metabotropic glutamate receptors (mGlu receptors)

spinal cord

DHPG

LY393053

pain

acetic acid-writhing

DORSAL HORN NEURONS

CENTRAL-NERVOUS-SYSTEM

RAT-BRAIN

IN-VIVO

PHENYLGLYCINE DERIVATIVES

NOCICEPTIVE TRANSMISSION

MONOSYNAPTIC EXCITATION

SELECTIVE ANTAGONIST

MESSENGER-RNA

RESPONSES

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Title: Evaluation of the activity of a novel metabotropic glutamate receptor antagonist (+/-)-2-amino-2-(3-cis and trans-carboxycyclobutyl-3-(9-thioxanthyl acid) in the in vitro neonatal spinal cord and in an in vivo pain model
Creators: Y Chen
G Bacon
E Sher
BP Clark
MJ Kallman
RA Wright
BG Johnson
DD Schoepp
AE Kingston
Publication Details: NEUROSCIENCE, Vol.95(3), pp.787-793
Publisher: PERGAMON-ELSEVIER SCIENCE LTD
Date published: 01/01/2000
Date submitted: 17/05/2017
Identifiers: 99512983702346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

Evaluation of the activity of a novel metabotropic glutamate receptor antagonist (+/-)-2-amino-2-(3-cis and trans-carboxycyclobutyl-3-(9-thioxanthyl acid) in the in vitro neonatal spinal cord and in an in vivo pain model

Abstract

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