Enzyme kinetic and molecular modelling studies of sulphur-containing substrates of phenylalanine 4-monooxygenase

NG Patel; C Iliadou; B Boonyapiwat; DJ Barlow; B Forbes; SC Mitchell; GB Steventon

doi:10.1080/14756360701810280

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Enzyme kinetic and molecular modelling studies of sulphur-containing substrates of phenylalanine 4-monooxygenase

Journal article

Peer reviewed

Enzyme kinetic and molecular modelling studies of sulphur-containing substrates of phenylalanine 4-monooxygenase

NG Patel, C Iliadou, B Boonyapiwat, DJ Barlow, B Forbes, SC Mitchell and GB Steventon

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, Vol.23(6), pp.958-963

01/01/2008

DOI: https://doi.org/10.1080/14756360701810280

Abstract

Science & Technology

Life Sciences & Biomedicine

Biochemistry & Molecular Biology

Chemistry

Medicinal

Pharmacology & Pharmacy

BIOCHEMISTRY & MOLECULAR BIOLOGY

CHEMISTRY

MEDICINAL

Phenylalanine 4-monooxygenase

thioether substrates

S-oxidation

inhibition

computer modelling

CARBOXYMETHYL-L-CYSTEINE

CATALYTIC DOMAIN

HYDROXYLASE

3-(2-THIENYL)-L-ALANINE

TETRAHYDROBIOPTERIN

SPECIFICITY

MECHANISM

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Title: Enzyme kinetic and molecular modelling studies of sulphur-containing substrates of phenylalanine 4-monooxygenase
Creators: NG Patel
C Iliadou
B Boonyapiwat
DJ Barlow
B Forbes
SC Mitchell
GB Steventon
Publication Details: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, Vol.23(6), pp.958-963
Publisher: INFORMA HEALTHCARE
Date published: 01/01/2008
Date submitted: 17/05/2017
Identifiers: 99515316802346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

Enzyme kinetic and molecular modelling studies of sulphur-containing substrates of phenylalanine 4-monooxygenase

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