Contribution of CYP1A2 in the hepatic metabolism of melatonin: studies with isolated microsomal preparations and liver slices

DJ Skene; E Papagiannidou; E Hashemi; J Snelling; DFV Lewis; M Fernandez; C Ioannides

doi:10.1034/j.1600-079X.2001.310408.x

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Contribution of CYP1A2 in the hepatic metabolism of melatonin: studies with isolated microsomal preparations and liver slices

Journal article

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Contribution of CYP1A2 in the hepatic metabolism of melatonin: studies with isolated microsomal preparations and liver slices

DJ Skene, E Papagiannidou, E Hashemi, J Snelling, DFV Lewis, M Fernandez and C Ioannides

JOURNAL OF PINEAL RESEARCH, Vol.31(4), pp.333-342

01/11/2001

DOI: https://doi.org/10.1034/j.1600-079X.2001.310408.x

Abstract

Science & Technology

Life Sciences & Biomedicine

Endocrinology & Metabolism

Neurosciences

Physiology

Neurosciences & Neurology

ENDOCRINOLOGY & METABOLISM

NEUROSCIENCES

PHYSIOLOGY

CYP1A2

cytochrome P450

enzyme induction

liver slices

melatonin

6-sulphatoxymelatonin

ORAL MELATONIN

RAT

CYTOCHROME-P-450

INDUCTION

ENZYMES

FLUVOXAMINE

BIOAVAILABILITY

HYDROXYLATION

SELECTIVITY

INHIBITION

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Title: Contribution of CYP1A2 in the hepatic metabolism of melatonin: studies with isolated microsomal preparations and liver slices
Creators: DJ Skene
E Papagiannidou
E Hashemi
J Snelling
DFV Lewis
M Fernandez
C Ioannides
Publication Details: JOURNAL OF PINEAL RESEARCH, Vol.31(4), pp.333-342
Publisher: MUNKSGAARD INT PUBL LTD
Date published: 01/11/2001
Date submitted: 17/05/2017
Identifiers: 99516097902346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

Contribution of CYP1A2 in the hepatic metabolism of melatonin: studies with isolated microsomal preparations and liver slices

Abstract

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