Complement C5a-C5aR interaction enhances MAPK signaling pathway activities to mediate renal injury in trichloroethylene sensitized BALB/c mice

J-X Zhang; W-S Zha; L-P Ye; F Wang; H Wang; T Shen; C-H Wu; Q-X Zhu

doi:10.1002/jat.3179

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Journal article

Complement C5a-C5aR interaction enhances MAPK signaling pathway activities to mediate renal injury in trichloroethylene sensitized BALB/c mice

J-X Zhang, W-S Zha, L-P Ye, F Wang, H Wang, T Shen, C-H Wu and Q-X Zhu

JOURNAL OF APPLIED TOXICOLOGY, Vol.36(2), pp.271-284

01/02/2016

DOI: https://doi.org/10.1002/jat.3179

Abstract

Science & Technology

Life Sciences & Biomedicine

trichloroethylene

C5a

C5aR

renal injury

MAPK

C5A RECEPTOR ANTAGONIST

LIVER-TUMOR INDUCTION

ACTIVATION

RATS

INHIBITION

TRICHLOROACETATE

DICHLOROACETATE

IMPAIRMENT

PROTECTS

FIBROSIS

Toxicology

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Title: Complement C5a-C5aR interaction enhances MAPK signaling pathway activities to mediate renal injury in trichloroethylene sensitized BALB/c mice
Creators: J-X Zhang
W-S Zha
L-P Ye
F Wang
H Wang
T Shen
C-H Wu
Q-X Zhu
Publication Details: JOURNAL OF APPLIED TOXICOLOGY, Vol.36(2), pp.271-284
Publisher: WILEY-BLACKWELL
Publication Date: 01/02/2016
Identifiers: 99513713702346; WOS:000368144500009
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

Complement C5a-C5aR interaction enhances MAPK signaling pathway activities to mediate renal injury in trichloroethylene sensitized BALB/c mice

Abstract

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