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Cardiosphere-derived cells improve function in the infarcted rat heart for at least 16 weeks--an MRI study.
Journal article   Peer reviewed

Cardiosphere-derived cells improve function in the infarcted rat heart for at least 16 weeks--an MRI study.

CA Carr, DJ Stuckey, JJ Tan, SC Tan, RS Gomes, P Camelliti, E Messina, A Giacomello, GM Ellison and K Clarke
PLoS One, Vol.6(10), pp.e25669-?
2011
DOI: https://doi.org/10.1371/journal.pone.0025669

Abstract

Animals Animals Newborn Cell Differentiation Ferric Compounds Green Fluorescent Proteins Heart Function Tests Magnetic Resonance Imaging Cine Myoblasts Cardiac Myocardial Infarction Rats Stem Cell Transplantation Time Factors Treatment Outcome
Endogenous cardiac progenitor cells, expanded from explants via cardiosphere formation, present a promising cell source to prevent heart failure following myocardial infarction. Here we used cine-magnetic resonance imaging (MRI) to track administered cardiosphere-derived cells (CDCs) and to measure changes in cardiac function over four months in the infarcted rat heart.
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http://www.ncbi.nlm.nih.gov/pubmed/22043289View
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