Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study.

JB Richards; F Rivadeneira; M Inouye; TM Pastinen; N Soranzo; SG Wilson; T Andrew; M Falchi; R Gwilliam; KR Ahmadi; AM Valdes; P Arp; P Whittaker; DJ Verlaan; M Jhamai; V Kumanduri; M Moorhouse; JB van Meurs; A Hofman; HA Pols; D Hart; G Zhai; BS Kato; BH Mullin; F Zhang; P Deloukas; AG Uitterlinden; TD Spector

doi:10.1016/S0140-6736(08)60599-1

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$Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study.$

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Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study.

JB Richards, F Rivadeneira, M Inouye, TM Pastinen, N Soranzo, SG Wilson, T Andrew, M Falchi, R Gwilliam, KR Ahmadi, …

Lancet, Vol.371(9623), pp.1505-1512

03/05/2008

DOI: https://doi.org/10.1016/S0140-6736(08)60599-1

Abstract

Alleles

Bone Density

Chromosomes

Human

Pair 11

Chromosomes

Human

Pair 8

Female

Fractures

Bone

Gene Expression

Genetic Markers

Genome

Human

Genotype

Humans

LDL-Receptor Related Proteins

Low Density Lipoprotein Receptor-Related Protein-5

Lumbar Vertebrae

Male

Middle Aged

Osteoporosis

Osteoprotegerin

Polymorphism

Single Nucleotide

Osteoporosis is diagnosed by the measurement of bone mineral density, which is a highly heritable and multifactorial trait. We aimed to identify genetic loci that are associated with bone mineral density.

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Title: Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study.
Creators: JB Richards
F Rivadeneira
M Inouye
TM Pastinen
N Soranzo
SG Wilson
T Andrew
M Falchi
R Gwilliam
KR Ahmadi
AM Valdes
P Arp
P Whittaker
DJ Verlaan
M Jhamai
V Kumanduri
M Moorhouse
JB van Meurs
A Hofman
HA Pols
D Hart
G Zhai
BS Kato
BH Mullin
F Zhang
P Deloukas
AG Uitterlinden
TD Spector
Publication Details: Lancet, Vol.371(9623), pp.1505-1512
Date published: 03/05/2008
Date submitted: 17/05/2017
Identifiers: 99513860702346
Academic Unit: University of Surrey
Language: English
Resource Type: Journal article

Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study.

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